Surgical Septal Myectomy Versus Percutaneous Transluminal Alcohol Septal Ablation in Patients With Hypertrophic Obstructive Cardiomyopathy
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The aim of this randomized trial is to compare the improvement in exercise capacity among patients with highly symptomatic hypertrophic obstructive cardiomyopathy despite optimal medical treatment who undergo alcohol septal ablation (ASA) or surgical septal myectomy (SSM).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 75
Healthy Volunteers: f
View:
• Age between 40-75 years including 40 and 75 years of age
• HOCM eligible for both SSM and ASA by a heart team (multidisciplinary team) and core lab.
• Left ventricle outflow tract (LVOT) obstruction \> 30mmHg at rest or during physiological provocation by transthoracic echocardiogram
• Symptomatic (New York Heart Association classification (NYHA) \>1 or Canadian Cardiovascular Society (CCS) class \>1) and/or syncope due to HOCM
Locations
Other Locations
Netherlands
St. Antonius Hospital
RECRUITING
Nieuwegein
Time Frame
Start Date: 2021-06-30
Estimated Completion Date: 2026-05-01
Participants
Target number of participants: 100
Treatments
Active_comparator: Alcohol Septal Ablation
Active_comparator: Surgical Septal Myectomy
Related Therapeutic Areas
Sponsors
Leads: St. Antonius Hospital
Collaborators: Erasmus Medical Center